JKK MUNIRAJAH MEDICAL RESEARCH FOUNDATION'S

ANNAI JKK SAMPOORANI AMMAL COLLEGE OF PHARMACY

Approved by PCI,New Delhi, Affiliated to The Tamilnadu Dr. M.G.R.Medical University, Chennai

Pharmaceutical Chemistry & Analysis

Introduction

                                                   DF0A8885.JPG (8.68 MB)

The department of Pharmaceutical Chemistry was established in 2008. Since then, the Department has been actively involved in imparting a relevant knowledge base and technical skills in the field of pharmaceutical chemistry; offering engrossing research activities in the field of industrial research, development of eco-friendly and “green chemistry methodologies”, and fundamental academic research.

The department offers excellent infrastructure with sophisticated equipment and well equipped laboratories; as well as  knowledge in the form of a vast collection of relevant books and journals. Moreover, extensive publications in national and international journals of repute, speaks volumes of the department's commitment to research activities.

Pharmaceutical Analysis was established in 2007. The courses were designed to provide industry ready professionals for the analysis and quality control of pharmaceuticals with an appropriate skill set, knowledge base and practical expertise.

State of the art infrastructure facilities are available in the department to provide knowledge and skills in handling the sophisticated instruments.

Students will learn about the qualitative and quantitative determination of APIs and pharmaceutical formulations using various analytical techniques like titrimetric, electrochemical spectroscopic and chromatographic methods.

The department of Pharmaceutical Chemistry & Analysis is primarily involved in providing strong foundation in fundamentals of different branches of chemistry viz. Organic chemistry, Inorganic chemistry, Biochemistry, Medicinal Chemistry, Natural product chemistry and Analytical Chemistry. M. Pharm Pharmaceutical analysis started in 2007 and chemistry Branch was started in 2008.

The objective of the department is to provide profound theoretical and practical knowledge to the students and to shape them into professionals with technical competence by intensive training.

Our mission is to instill confidence in our students by adopting an interactive teaching methodology through which they are made to understand the basics of chemistry and to create a conductive environment that will  make them skilled chemists and analysts.  The faculty of this department is well experienced and highly qualified with a dedication to teaching. The entire faculty has the exposure and opportunity to carry out research. The department has more than 50 original research articles published in reputed journals.

The department has all the basic and advanced features like well-ventilated spacious laboratories with water and gas connections, a fume-free environment, glass wares including custom-designed vessels etc. The department has HPTLC, HPLC, FTIR and UV spectrophotometers, digital melting point apparatus, microwave reactor, reaction dry bath, hot air oven, vacuum oven, digital mixers and stirrers, high end filtration equipment’s and other instruments to carry out research.

The department has identified core areas of research mainly in medicinal chemistry in the fields of cancer, diabetes, inflammation and chemotherapy of microbial diseases. The prime motto of our research is to identify a lead molecule either of synthetic or natural origin and to optimize the lead to achieve desirable pharmacodynamics and pharmacokinetic properties. The methods to identify the lead applied in our department includes design, synthesis, SAR, characterization and screening of novel organic molecules using traditional as well as cutting edge technologies like high throughput screening and molecular modelling. Lead optimization is carried out using computational methods.

Our strategy for achieving global standards to develop a "Drug design and synthesis research laboratory" with excellent facilities at par with industrial standards and to possess accreditation of government research organizations, pharmaceutical industries and international standard organizations.

The department of Pharmaceutical Analysis aspires to focus on the development of analytical methods that combine novel apparatus and approaches with existing ones. Basic research on the identity, purity, content, and stability of starting materials, excipients, and active medicinal substances is involved. The department teaches and trains postgraduate students in analytical sciences relevant to the qualitative and quantitative estimation of natural, synthetic substances and biological samples in various matrices using spectroscopy, chromatography, and analytical procedures.

Pharmaceutical Analysis is a branch of practical chemistry that involves a series of process for identification, determination, quantification and purification of a substance, separation of the components of a solution or mixture, or determination of structure of chemical compounds. The department of Pharmaceutical Analysis was established in 2007. The courses were designed to provide industry ready professionals for the analysis and quality control of pharmaceuticals with appropriate skill set, knowledge base and practical expertise. The department is also recognized for its Ph.D. research program. The research laboratory in the department is equipped with sophisticated analytical instruments like High Performance Liquid Chromatography (HPLC) with different detector configurations (Photo diode array detector, Dual Wavelength UV Detector and UV-VIS detectors), UV – VIS Spectrophotometer, FT- IR Spectrophotometer, Fluorimeters, Flame Photometers etc. The departmental activities are supported by well qualified and trained academicians

Thrust Areas:

  • Analytical and Bio analytical method development and validation
  • QbD based analytical method optimization
  • Impurity Profiling
  • Development and validation of stability indicating analytical methods
  • Food and cosmetic analysis
  • Application of green chemistry for rapid analysis of drugs
  • Standardization of Herbal formulations
  • Development and evaluation of drugs/ formulations for heavy metal toxicity.

Vision & Mission

Vision

Pharmaceutical chemistry & Analysis department aims to develop highly competent, professional, expert pharmacist with ample scientific background that contributes to the new drug development through Chemical Research.

Mission

The mission of Pharmaceutical chemistry & Analysis department is to give the students, extensive and varied scientific background, and a rewarding and challenging program of study.

HOD Profile

Name : Dr. N. Senthilkumar,

Qualification : M.Pharm., PhD

Department : Pharmaceutical Chemistry

Designation : Professor / Principal

Date of Joining : 19.09.1992

Area of Research : Pharmaceutical Chemistry , Pharmacology, Pharmaceutical Analysis, Pharmaceutics & Clinical Pharmacy etc.,


principal-passportsize (1).jpg (246 KB)

Dr. N. Senthilkumar, M.Pharm., PhD

Professor / Principal.

Field of Specialization

Pharmaceutical Chemistry

Phone No.

9789456750

E-Mail

senthilkumarjkkm@gmail.com

Residential Address

8/1188-E EB Colony, Lakshmi Nagar,

Sri Vasavi College (Po),

Erode, Tamilnadu.

Experience

30 Years

Blood Group

B-ve

Publication Details

International : 49

National : 43

Project details

UG : 25

PG : 35

Ph.D., Guideships : 16

Book Published : 4

Patent Details : 1

Awards received : 1

Conference/ Workshop/ Symposium/ Seminar/FDP Attended : 12

Conference/ Workshop/ Symposium/ Seminar/FDP Conducted : 15

Resource Person in Conference/ Workshop/ Symposium/ Seminar/FDP : 4

Membership Details : APTI / IPA / FIP/ IACP

 

Staff

Research Area

           The R&D Cell coordinates sponsored research, collaborative research and industrial consulting projects at JKKMMRF’s Annai JKK Sampoorani Ammal college of Pharmacy. Through such projects, the Institute strengthens the R&D capabilities of the faculty and students and participates in Industry-relevant problem solving. The Institute has experienced academicians and researchers from various R&D units in the country. In making our vision and mission a reality, the Institution has taken the initiative to promote innovative ideas of faculty and students and collaborate with Industries for mutual benefit. Committed to excellence in fundamental research as well as the development of innovative technologies for the future, the Institution offers a quality research training experience for its students.

The Institute maintains its relevance to world-class research by linking with industry and academia through local and international research networks.

Design and synthesis of small drug-like molecules using computational tools for the treatment of cancer, depression and bacterial infections.

 

Conventional and solid/liquid phase combinatorial synthesis, including microwave-assisted synthesis of novel chemical entities.

 

Design and development of nano particulate drug conjugates for targeted drug delivery.

Identification and isolation of structurally novel and biologically active natural compounds for human diseases from medicinal plants.

 

Research Activities

 

ü     Received a grant of Rs.15,000/- from The Tamil Nadu Dr.M.G.R. Medical University, Chennai for conducting a conference on 'Approaches in Combinatorial Chemistry.. Challenging and Perspectives' on 05.04.2019. 

ü     Received a grant of Rs.15,000/- from The Tamil Nadu Dr.M.G.R. Medical University, Chennai for conducting a conference on 'Computational Tool in Medicinal Chemistry: Concept and Applications' on 17.06.2022. 

The Department of Pharmaceutical Chemistry extends its wings to computational (pharmacophore-based virtual screening, 3D-QSAR studies, molecular docking and molecular dynamics) studies and small molecule synthesis using microwave and solid-phase synthesis. The department faculty members have high expertise in computational drug design tools and small molecule drug discovery (synthetic and natural) strategies. Research scholars and postgraduate students are actively engaged in drug discovery research. Some of the key research activities of the department are listed below.

ü  Design and development of inhibitors of histone deacetylase & oestrogen receptor alpha, topo poisons and d-carboline analogues as anticancer agents.

ü  Design and development of ER, HER2, PARP, BRCA1 mimetic s for breast cancer therapy

ü  Design and synthesis of novel lead molecules against multiple targets of SARS CoV-2

ü  Central Neuroprotective evaluation of heterocyclic compounds as p2x7 receptor antagonists

ü  Design and development of gamma-secretase inhibitors for the treatment of breast cancer.

The Department has well-equipped research laboratories with several advanced instruments and drug discovery software tools for the synthesis of new chemical entities (NCEs).The laboratories are designed and equipped with several unique features and facilities including a central ventilation system and very sophisticated fume hoods attached to nitrogen, vacuum and water supply.

Instruments for synthesis

 

ü  Precision Digital Balance

ü  Catalyst Microwave synthesizer

ü  Mini Block Parallel Synthesizer

ü  Carousel Reaction Station

ü  NuTech Microwave synthesizer

 

Instruments for chemical characterization

 

ü  Buchi Rotary Evaporator

ü  Precision Digital Melting Point Apparatus

ü  Perkin Elmer Spectrum-2 FT-IR

Software tools for drug discovery

 

ü  Schrodinger molecular modelling suite (Glide, Prime, Phase,Desmond)

ü  Sybyl molecular modelling suite

ü  Biovia drug discovery studio molecular modelling suite

ü  Autodock, PyRx, Gromacs

 

RESEARCH GUIDE

SNo

 Name of the Supervisor

 University

 Department

 Research Area

 E-Mail-ID

 

 

  1

 

 

Dr. N.Senthilkumar

The Tamil nadu Dr MGR Medical Unuversity

Pharmaceutical Chemistry

Pharmaceutical science

senthilkumarjkkm@gmail.com

 

 

  2

 

 

Dr.T. Venkatachalam

The Tamil nadu Dr MGR Medical Unuversity

Pharmaceutical Chemistry

Pharmaceutical science

venkatachalammpharm@yahoo.co.in

 

 

  3

 

 

Dr. P.Kalaiselvi

The Tamil nadu Dr MGR Medical Unuversity

Pharmaceutical analysis

Pharmaceutical science

kalaimpa@gmail.com

 

Events

ACDEMIC YEAR : 2022 - 23
DATE NAME OF THE WORKSHOP/SEMINAR DETAILS OF THE RESOURCE PERSON WITH DESIGNATION NO. OF PARTICIPANTS
17/06/2022 Computational Tool In Medicinal Chemistry : Concept And Applications Dr. KRISHNARAJ M.Pharm., Ph.D., R&D, Himalaya Wellness Company, Bangalore. 250
ACDEMIC YEAR : 2021 - 22
DATE NAME OF THE WORKSHOP/SEMINAR DETAILS OF THE RESOURCE PERSON WITH DESIGNATION NO. OF PARTICIPANTS
18/06/2021 Seminar on Medicinal Plants for Treatment of COVID-19 Dr.P. BALAN, M.Pharm., Ph.D., Professor, Erode College Of Pharmacy, Erode. 400
23/07/2021 Workshop on Herbal Nano Technology-An Update Dr.A.SUMATHI,M.Pharm, Ph.D., Nandha College Pharmacy Of, Erode 116
10/9/2021 Complement System-An Overview Dr. N. KIRUTHIGA,M.Pharm Ph.D., Kmch College Of Pharmacy Coimbatore. 350
27/10/2021 Important Tips to crack GPAT 2022 & developments in pharmaceutical industry Mr. R.RAJAGURU M.PHARM.,(Ph.D)., Senior Scientist, R&D,Graviti Pharma, Hyderabad 160
ACDEMIC YEAR : 2020 - 21
DATE NAME OF THE WORKSHOP/SEMINAR DETAILS OF THE RESOURCE PERSON WITH DESIGNATION NO. OF PARTICIPANTS
5/3/2021 Seminar on Effective Pedagogy Principle in Teaching Dr V.S.THIRUVENGADARAJAN M.Pharm., Ph.D., KMCH college of Pharmacy, Coimbatore 200
30/04/2021 Geographical Indication & copyright for Drugs Dr.P.DHEEN KUMAR, M.PHARM, PhD Principal GP College of Pharmacy, Triupattur 350
ACADEMIC YEAR : 2019 - 20
DATE NAME OF THE WORKSHOP/ SEMINAR DETAILS OF THE RESOURCE PERSON WITH DESIGNATION NO. OF PARTICIPANTS
02/04/2020 - 03/04/2020 Descriptive research: Observations, Surveys & Case Studies Dr.P. BALAN, M.PHARM PhD Professor, The Erode College Of Pharmacy, Erode. 400
20/03/2020 Seminar on Identify the Role of an Entrepreneur Dr.T.VENKATACHALAM, M.PHARM PhD Professor, Jkkmmrf’s Annai Jkk Sampooraniammal College Of Pharmacy, Komarapalayam. 350
15/02/2020 Seminar on Data Collection Tools in Research Mr.R.Seetharaman,MBA Excel College of pharmacy Komarapalayam. 350
03/1/2020 Co-operation between IP offices, Customs & other Enforcement agencies Dr .K.SUMATHI, M.PHARM, PhD Assistant Professor, JKKMMRF’s Annai Jkk Sampooraniammal College Of Pharmacy, Komarapalayam . 250
28/12/2019 Workshop on Juristions of Trade Secrets Dr.M.DHANAMANI, M.PHARM, Ph.D Sri Ramakrishna College Of Pharmacy, Coimbatore. 175
19/10/2019 Assessment of the effectiveness of environmental Sanitation in the control of dengue Dr.S.SARANYA SEKAR,MBBS General Medicine Dr.N.NANDHA KUMAR, MBBS, D.ORTHO 350
26/07/2019 - 27/07/2019 Qualitative & Quantitative research Dr. K. SRINIVASAN, M.PHARM, PhD Nandha College Of Pharmacy, Erode.. 350
28/06/2019 Protection of IPR for enforcement Officials Dr .N. SENTHIL KUMAR, M.PHARM, PhD Principal, JKKMMRF’s Annai Jkk Sampooraniammal College Of Pharmacy, Komarapalayam. 275
ACDEMIC YEAR : 2018 - 19
DATE NAME OF THE WORKSHOP / SEMINAR DETAILS OF THE RESOURCE PERSON WITH DESIGNATION NUMBER OF PARTICIPANTS
08/04/2019-09/04/2019 Geographical Indication & copyright for Drugs Dr.P.DHEEN KUMAR,M.PHARM, PhD Principal GP College of Pharmacy, Triupattur 400
15/02/2019 Seminar on Enforcement of IP Rights Dr .N.SENTHILKUMAR, M.Pharm ,PhD, Principal, JKKMMRF’S Annai JKK Sampoorani Ammal College of Pharmacy, komarapalayam. 350
31/01/2019 Symposium on Intellectual Property rights Dr.P.VaijanthiMala, M.Pharm ,PhD, SSM College Of Pharmacy , Jambai 350
03/01/2019-04/01/2019 Research Methodology: Nature, Purpose of study, design & data type Dr.Durai Anand Kumar, M.Pharm,PhD Dr.Yuvaraj, M.pharm, PhD.Jss college of pharmacy 250
7/12/2018 Procedure, Rules and Regulations to Register a Business DR. K. SUBRAMANIAN M.Com, M.Phil, PhD Erode Arts College, Erode. & Mrs. K. SATHYASUNDARIsMCA JKKMMRF’s College of Pharmacy 350
19/09/2018 Workshop: Innovation and Technological Entrepreneurship Mr.R.Ferdinand,MPT(ortho) & Mrs. Kokilavani,MPT(Cardio) JKKMMRF's College Of Physiotherapy, Komarapalayam 250
ACDEMIC YEAR : 2017 - 18
DATE NAME OF THE WORKSHOP/SEMINAR DETAILS OF THE RESOURCE PERSON WITH DESIGNATION NUMBER OF PARTICIPANTS
04/04/2018 - 05/04/2018 Research Designs & Methodologies related to Regulatory affairs Dr.JAGATHEESWARAN,MOT,PhD & Mr.Mohanraj,MOT, JKKMMRF's College Of Occupational Therapy, Komarapalayam 400
08/02/2018 - 09/02/2018 Current challenges in IPRs and Biotechnology Mrs.B.ANBARASI, M.Pharm., JKKMMRF’S Annai jkk Sampoorani Ammal College of Pharmacy, Komarapalayam. Dr. KANNAN,MPT,PhD JKKMMRF's College Of Physiotherapy, Komarapalayam 350
22/12/2017 Seminar on Understand the risk of Becoming an entrepreneur Dr.P.KALAISELVI M.Pharm.,Ph.D., & Mr.SURESHKANAN, M.Pharm JKKMMRF’S Annai jkk Sampoorani Ammal College of Pharmacy, Komarapalayam. 350
24/11/2017 - 25/11/2017 Tips to consider while selecting a research Methodology Dr.T.VENKATACHALAM, M.PHARM PhD & Dr.M.CHITRA M.PHARM., PhD., JKKMMRF’S Annai jkk Sampoorani Ammal College of Pharmacy, Komarapalayam 250
10/8/2017 Workshop: Trade Secrets of Pharmaceutical Preparations Dr .K.SUMATHI, M.PHARM, PhD., JKKMMRF’S Annai jkk Sampoorani Ammal College of Pharmacy, Komarapalayam. 350

M.PHARM XL MPATPC MC.xlsx (39 KB) 

M.PHARM (PHARMACEUTICAL CHEMISTRY)

PROGRAMME EDUCATIONAL OUTCOMES (PEOs)

PEO - 1

To produce pharmacy post-graduates with strong fundamental concepts and high technical competence in pharmaceutical sciences and technology, who shall be able to use these tools in pharmaceutical industry and/or institutes where ever necessary for success.

PEO - 2

To promote the development of trained human resource in Pharmaceutical Sciences for dissemination of quality education with highly professional and ethical attitude, strong communication skills, effective skills to work in a team with a multidisciplinary approach.

PEO - 3

To generate potential knowledge pools with interpersonal and collaborative skills to identify, assess and formulate problems and execute the solution in closely related pharmaceutical industries.

PROGRAMME SPECIFIC OUTCOMES (PSOs)

PSO - 1

Independently carry out research / investigation, developmental work related to new chemical entities, develop the synthetic strategies and drug design proposals.

PSO - 2

Gain knowledge of practical techniques and advanced techniques to solve the problems in isolation, separation, purification and confirmation of chemical entities.

 

PROGRAMME OUTCOMES (PO)

M.PHARM (PHARMACEUTICAL CHEMISTRY)

PO - 1

To acquire advanced knowledge of Analytical Techniques, Pharmaceutical Chemistry, Medicinal Chemistry, Drug Design, Research Methodology, and Drug Regulatory Affairs.

PO - 2

To develop research aptitude to identify and provide valid conclusions for pharmaceutical problems by utilizing the technical skill gained through training and experimentation.

PO - 3

To impart knowledge on single-step and multi-step synthetic reactions, identification and interpretation of intermediates, and conversion into final products.

PO - 4

To develop a synthetic route for small molecules.

PO - 5

To apply all the naming reactions in the multistep process in the manufacturing of drugs and drug intermediates special reactive intermediates including carbenes, carbanions, and free radicals.

PO - 6

Will be able to design and carry out scientific experiments as well as accurately record and analyze the results of such experiments.

PO - 7

To Operate equipment/instruments required for the characterization and quantification of organic compounds.

PO - 8

To Design new techniques of organic synthesis using green chemistry.

PO - 9

To Design and implement research projects independently.

 

COURSE OUTCOMES

M.PHARM (PHARMACEUTICAL CHEMISTRY ) - YEAR - I (SEMESTER - I)

MPC101T

Modern Pharmaceutical Analytical Techniques

CO - 1

Understood the basic knowledge on assay of single and multiple component pharmaceuticals by using various analytical instruments.

CO - 2

Developed the theoretical knowledge on various instrumental techniques available for analysis of organic substances by using analytical instruments.

CO - 3

Improved skills in selecting the suitable techniques for analysis of drugs and pharmaceuticals.

CO - 4

The students can able to Interpret spectra of UV‐visible, IR, NMR and Mass to identity the given compound.

CO - 5

The students can able to describe the general methods for separation and purification of components from a mixture and their application to pharmaceutical industry.

 

M.PHARM (PHARMACEUTICAL CHEMISTRY ) - YEAR - I (SEMESTER - I)

MPC102T

Advanced   Organic Chemistry -I

CO - 1

Applied the knowledge in asymmetric synthesis

CO - 2

Understood the concepts of aromaticity and reaction intermediates.

CO - 3

Gained detailed knowledge regarding the reactions, mechanisms and their relative reactivity Learn mechanism of electrocyclic and pericyclic reactions.

CO - 4

Enhanced the knowledge on various reactions and synthetic applications.

CO - 5

The students have been introduced to organic reaction, including isolating, purifying, and characterizing the product

 

M.PHARM (PHARMACEUTICAL CHEMISTRY ) - YEAR - I (SEMESTER - I)

MPC103T

Advanced Medicinal chemistry

CO - 1

Applied basic knowledge of pharmaceutical chemical aspects of drugs that are in clinical use in defining, analyzing and proposing actions related to the research and implementation of new laboratory methods for detecting and monitoring diseases and effects or efficacy of the therapy.

CO - 2

Learnt the discovery of lead molecules and rational drug discovery models.

CO - 3

Development of enzyme inhibitors

CO - 4

Provided insight knowledge on prodrug design and analog design.

CO - 5

Gained advance knowledge on enzyme inhibitors.

 

M.PHARM (PHARMACEUTICAL CHEMISTRY ) - YEAR - I (SEMESTER - I)

MPC104T

Chemistry of Natural Products

CO - 1

Learnt to explore the natural lead compounds for the treatment of diseases like cancer.

CO - 2

Understood various principles of extraction methods and factors influencing the choice of extraction.

CO - 3

Can able to describe the extraction of plant drugs by microwave assisted synthesis, their merits and demerits.

CO - 4

Gained detailed knowledge advanced knowledge on importance and structural

elucidation of steroids, terpenoids and antibiotics.

CO - 5

The students have been introduced to structure of amino acids, peptides, proteins, alkaloids and purines.

 

M.PHARM (PHARMACEUTICAL CHEMISTRY ) - YEAR - I (SEMESTER - I)

MPC105P

Pharmaceutical Chemistry Practical I

CO - 1

The students have been recalled and relate the principle of spectroscopy, chromatography and other commonly used instrumental methods of analysis.Train the students and to give hands on training on these sophisticated instruments.

CO - 2

Performed quantitative & qualitative analysis of drugs using various analytical instruments like UV‐visible and IR spectrophotometer and HPLC.

CO - 3

Planned and selected lab experiments using appropriate analytical skills. Evaluated the quantity of a drug in a given formulation.

CO - 4

Practiced them on solving spectral problems and generate a comprehensive analytical report on the findings

CO - 5

Gained detailed knowledge on interpret spectra of UV‐visible, IR, NMR and Mass to identity the given compound.

 

M.PHARM (PHARMACEUTICAL CHEMISTRY ) - YEAR - I (SEMESTER - II)

MPC201T

Advanced   Spectral Analysis

CO - 1

Student will learn the various hyphenated analytical instrumental techniques

CO - 2

Student will deals with different analytical data from different principle instrument

CO - 3

Student will expose to different analytical data like LC-MS, GC-MS, ATR-IR, DSC etc. theoretically and practically.

CO - 4

Fellow student will able to handle different analytical data to predict the unknown structures

CO - 5

At the end of the course student should know to handle different hyphenated instruments data

 

M.PHARM (PHARMACEUTICAL CHEMISTRY ) - YEAR - I (SEMESTER - II)

MPC202T

Advanced   Organic Chemistry -II

CO - 1

Memorized the applications of synthetic reagents.

CO - 2

Understood various types of catalysis like homogenous catalysis and heterogeneous catalysis.

CO - 3

Understood molecular arrangements and their applications.

CO - 4

Gained the sound knowledge on chemistry of peptides.

CO - 5

Learnt the principles of green chemistry

 

M.PHARM (PHARMACEUTICAL CHEMISTRY ) - YEAR - I (SEMESTER - II)

MPC203T

Computer Aided Drug Design

CO - 1

Understood Role of CADD in drug discovery.

CO - 2

Learnt Different CADD techniques and their applications.

CO - 3

Applied various strategies to design and develop new drug like molecules

CO - 4

The students can able to Work with molecular modeling software’s to design new drug molecules.

CO - 5

The students can able to Illustrate the insilico virtual screening protocols, pharmacophore modeling and mapping.

 

M.PHARM (PHARMACEUTICAL CHEMISTRY ) - YEAR - I (SEMESTER - II)

MPC204T

Pharmaceutical ProcessChemistry

CO - 1

Understood various strategies of scale up process of apis and intermediates.

CO - 2

Summarized unit operations like extraction, filtration and crystallization.

CO - 3

Learnt kinetics and mechanism of nitration, halogenation and oxidation

CO - 4

The students can able to analysis of case studies on industrial reduction process.

CO - 5

Can able to Differentiate Aerobic and Anaerobic fermentation

 

M.PHARM (PHARMACEUTICAL CHEMISTRY ) - YEAR - I (SEMESTER - II)

MPC205P

Pharmaceutical Chemistry Practical II

CO - 1

Students have gained knowledge on synthesis of APIs and intermediates by different synthetic techniques

CO - 2

Performed Interpretation of organic compounds using IR, NMR, CNMR and Mass spectra And Comparison of absorption spectra by UV and Wood ward – Fieser rule

CO - 3

The students can able to compute with molecular modeling software’s to design new drug molecules.

CO - 4

The students have been introduced to Summarize 2D and 3D QSAR studies.

CO - 5

Understood concept of virtual and docking based experiments

 

M.PHARM  - YEAR - II (SEMESTER - III)

COMMON TO ALL BRANCHES

MRM 301T

Research Methodology and Biostatistics

CO - 1

Students should understand a general definition of research design

CO - 2

Students should be able to identify the overall process of designing a research study and the use of various statistical test involved

CO - 3

Students should be familiar with human ethical issues in educational research, including those issues that arise in using quantitative and qualitative research

CO - 4

Students should know the guidelines in performing animal study and maintenance of animal house.

CO - 5

Students should be familiar with declaration of Helsinki

 

M.PHARM  - YEAR - II (SEMESTER - III & IV)

COMMON TO ALL BRANCHES

 

JOURNAL CLUB

CO - 1

Able to collect relevant literature and critically evaluate them

CO - 2

Learnt to make a PPT presentation scientifically and deliver the same

CO - 3

Able to involve effectively in post presentation  discussion

 

M.PHARM  - YEAR - II (SEMESTER - III & IV)

COMMON TO ALL BRANCHES

 

DISCUSSION / PRESENTATION (PROPOSAL PRESENTATION)

CO - 1

Able to select research topic through literature review  

CO - 2

Able to design research methodology

CO - 3

Able to Present the selected research proposal  convincingly

 

M.PHARM  - YEAR - II (SEMESTER - III & IV)

COMMON TO ALL BRANCHES

 

RESEARCH WORK

CO - 1

Able to carry out research work scientifically following research ethics

 

CO - 2

Able to collect date, interpret them using appropriate statistical tools and arrive at conclusion scientifically

CO - 3

 Able to document the research work in the form of thesis in an acceptable format

 

M.PHARM (PHARMACEUTICAL ANALYSIS)

PROGRAMME EDUCATIONAL OUTCOMES (PEOs)

PEO - 1

To produce pharmacy post-graduates with strong fundamental concepts and high technical competence in pharmaceutical sciences and technology, who shall be able to use these tools in pharmaceutical industry and/or institutes where ever necessary for success.

PEO - 2

To promote the development of trained human resource in Pharmaceutical Sciences for dissemination of quality education with highly professional and ethical attitude, strong communication skills, effective skills to work in a team with a multidisciplinary approach.

PEO - 3

To generate potential knowledge pools with interpersonal and collaborative skills to identify, assess and formulate problems and execute the solution in closely related pharmaceutical industries.

PROGRAMME SPECIFIC OUTCOMES (PSOs)

PSO - 1

To know the science of detection of impurities, impurities in pharmaceutical formulations, impurity profiling, stability testing of phytopharmceuticals and their protocol development.

PSO - 2

To know the Pharmacopieal assays by spectroscopical methods, calibration techniques, determination of preservatives, vitamin contents in drugs and foods.

 

PROGRAMME OUTCOMES (PO)

M.PHARM (PHARMACEUTICAL ANALYSIS)

PO - 1

Design and conduct analytical experiments for effective quality control system and validate the instruments used in Pharma industry.

PO - 2

Utilize tools and skills to perform analytical research work using modern techniques.

PO - 3

Use knowledge and abilities to solve problem in pharmaceutical quality system.

PO - 4

Expand the theoretical knowledge on various instrumental techniques available for analysis of organic substances and Acquire skills in identifying the impurities in combinational drugs.

PO - 5

Exhibit behavior and moral values that required for a pharmaceutical analyst at the satisfaction of corporate industry, other health care providers.

PO - 6

Demonstrate the ability to work in team by combining individual strength, team dynamics and emotional intelligence.

PO - 7

Acquire skills in selecting the suitable techniques for analysis of drugs and Compare different techniques/technologies to assess and evaluate dosage forms for better quality.

PO - 8

Identify strategies for effective communication system to undertake multidisciplinary area at the interface of analytical method development.

 

COURSE OUTCOMES

M.PHARM (PHARMACEUTICAL ANALYSIS ) - YEAR - I (SEMESTER - I)

MPA101T

Modern   Pharmaceutical Analytical Techniques

CO - 1

Understood the basic knowledge on assay of single and multiple component pharmaceuticals by using various analytical instruments

CO - 2

Developed basic practical skills using instrumentation techniques

CO - 3

Students have the skills in selecting the suitable techniques for analysis of drugs and pharmaceuticals

CO - 4

Can able to expand the theoretical knowledge on various instrumental techniques available for analysis of organic substances

CO - 5

Applied the knowledge learnt in developing new procedures of their own design

 

M.PHARM (PHARMACEUTICAL ANALYSIS ) - YEAR - I (SEMESTER - I)

MPA102T

Advanced     Pharmaceutical Analysis

CO - 1

The student understood the concepts of Impurity profiling

CO - 2

The students gained appropriate knowledge about appropriate analytical skills required for the analysis of impurities in the bulk drugs and various formulations.

CO - 3

The subject supply enough idea on the categorizing the impurities like(inorganic, organic and residual solvents)

CO - 4

It supports to understand the official and non-official methods to analyses the related substance

CO - 5

Critical analysis of analytical problem and selection of appropriate analytical tool for the quantification of chemicals and excipients

 

M.PHARM (PHARMACEUTICAL ANALYSIS ) - YEAR - I (SEMESTER - I)

MPA103T

Pharmaceutical Validation

CO - 1

The Students learnt on the importance of validation.& gain knowledge on how validation is carried for various components. Such as instrument validation, cleaning validation and process validation.

CO - 2

The student learns on the importance of patent and intellectual property rights

CO - 3

The students are trained on the qualification aspects of instruments

CO - 4

The importance of calibration to be performed for the instruments

CO - 5

The various validation aspects to be carried out in the industry

 

M.PHARM (PHARMACEUTICAL ANALYSIS ) - YEAR - I (SEMESTER - I)

MPA104T

Food Analysis

CO - 1

Student shall be able to understand various analytical techniques in the determination of Food constituents

CO - 2

Student shall be able to understand various analytical techniques in the determination of Food additives

CO - 3

Student shall be able to understand various analytical techniques in the determination of Finished food products

CO - 4

Student shall be able to understand various analytical techniques in the determination of Pesticides in food

CO - 5

Student shall be able to understand various analytical techniques in the determination of knowledge on food regulations

 

M.PHARM (PHARMACEUTICAL ANALYSIS ) - YEAR - I (SEMESTER - I)

MPA105P

Pharmaceutical Analysis Practical I

CO - 1

Students can able to Analyze and Simultaneously estimate multi component formulations by UV spectrophotometry

CO - 2

Learnt Hand on training of modern techniques like HPLC, IR, Flame, fluorimetry, GC and calibrated

CO - 3

Performed impurity profiling of drug and intermediate

CO - 4

Students can calibrate and validate of laboratory equipment

CO - 5

Can able to determine the physiochemical properties of food products by different analytical techniques

 

M.PHARM (PHARMACEUTICAL ANALYSIS ) - YEAR - I (SEMESTER - II)

MPA201T

Advanced   Instrumental Analysis

CO - 1

The students have learnt detailed interpretation pattern for the organic substances

CO - 2

The students have been introduced to theoretical aspects of the HPLC and GC techniques

CO - 3

Practical aspects and troubleshooting techniques for HPLC and GC techniques

CO - 4

Knowledge and skills in advanced instrumentation techniques for drug analysis

CO - 5

Theoretical aspects of hyphenated analytical techniques

 

M.PHARM (PHARMACEUTICAL ANALYSIS ) - YEAR - I (SEMESTER - II)

MPA202T

Modern Bio-Analytical Techniques

CO - 1

The subject provides enough knowledge to conduct bioequivalence studies

CO - 2

It upgrade the method to conduct bioequivalence study for formulations by utilizing the proper regulatory guidelines

CO - 3

It improvers ideas and updating information on the current trend in GCP and GLP

CO - 4

Pupil will be exposed to both theoretical and practical knowledge on quantification of analytic present in the biological fluids

CO - 5

The subject content presents better understanding on different analytic enrichment technique as well the instrumentation technique.

 

M.PHARM (PHARMACEUTICAL ANALYSIS ) - YEAR - I (SEMESTER - II)

MPA203T

Quality Control and Quality Assurance

CO - 1

Student shall be able to understand the cGMP aspects in a pharmaceutical industry

CO - 2

Student shall be able to understand the importance of documentation

CO - 3

Student shall be able to understand the scope of quality certifications applicable to Pharmaceutical industries

CO - 4

Student shall be able to understand the responsibilities of QA department

CO - 5

Student shall be able to understand the responsibilities of QC department

 

M.PHARM (PHARMACEUTICAL ANALYSIS ) - YEAR - I (SEMESTER - II)

MPA204T

Herbal    and  Cosmetic Analysis

CO - 1

Student shall be able to understand the determination of herbal remedies

CO - 2

Student shall be able to understand various herbal regulations

CO - 3

Student shall be able to understand various analytical techniques in the determination of herbal products

CO - 4

Student shall be able to understand the herbal monographs

CO - 5

Student shall be able to understand various herbal drug interactions

 

M.PHARM (PHARMACEUTICAL ANALYSIS ) - YEAR - I (SEMESTER - II)

MPA205P

Pharmaceutical Analysis Practical II

CO - 1

Performed Interpretation of medicinal drugs using IR, NMR, CNMR and Mass spectra And Comparison of absorption spectra by UV and Wood ward – Fieser rule

CO - 2

Bio molecules separation utilizing various sample preparation techniques and Quantitative analysis of components by different analytical techniques

CO - 3

Learnt protocol preparation for the conduct of BA/BE studies according to guidelines

CO - 4

Gained knowledge about quality control and quality assurance as per ICH guidelines

CO - 5

Quantitative analysis and determination of herbal and cosmetic products

 

PHARM.D

PROGRAMME EDUCATIONAL OUTCOMES (PEOs)

PEO - 1

The student will possess professional knowledge of pharmaceutical sciences and technology applicable in pharmaceutical, healthcare industry, community pharmacy and academia as per the requirement.

PEO - 2

With the grooming and knowledge gained, the student will play a major role as professional Pharmacist in the health care team and participate in implementation of various health programs at large.

PEO - 3

The student will inculcate the urge for lifelong learning and up - gradation to meet the needs of the profession and society.

PROGRAMME SPECIFIC OUTCOMES (PSOs)

PSO - 1

Apply and assess the literature and other research resources to provide evidence-based drug information that meets the needs of patients and other health care providers.

PSO - 2

Discuss how patients and care givers can obtain the most cost-efficient medications and related pharmaceuticals per patient-specific health insurance coverage options.

 

PROGRAMME OUTCOMES (PO)

PHARM D

PO - 1

Pharmacy Knowledge:  Possess knowledge and comprehension of the core and basic knowledge associated with the profession of pharmacy, including biomedical sciences; pharmaceutical sciences; behavioral, social, and administrative pharmacy sciences; and manufacturing practices.

PO - 2

Planning Abilities:   Demonstrate effective planning abilities including time management, resource management, delegation skills and organizational skills. Develop and implement plans and organize work to meet deadlines.

PO - 3

Problem analysis:  Utilize the principles of scientific enquiry, thinking analytically, clearly and critically, while solving problems and making decisions during daily practice. Find, analyze, evaluate and apply information systematically and shall make defensible decisions.

PO - 4

Modern tool us age:  Learn, select, and apply appropriate methods and procedures, resources, and modern pharmacy-related computing tools with an understanding of the limitations.

PO - 5

Leadership skills: Understand and consider the human reaction to change, motivation issues, leadership and team-building when planning changes required for fulfillment of practice, professional and societal responsibilities. Assume participatory roles as responsible citizens or leadership roles when appropriate to facilitate improvement in health and well-being.

PO - 6

Professional Identity:  Understand, analyze and communicate the value of their professional roles in society (e.g. health care professionals, promoters of health, educators, managers, employers, employees)

PO - 7

Pharmaceutical Ethics: Honor personal values and apply ethical principles in professional and social contexts. Demonstrate behavior that recognizes cultural and personal variability in values, communication and lifestyles. Use ethical frameworks; apply ethical principles while making decisions and take responsibility for the outcomes associated with the decisions.

PO - 8

Communication:  Communicate effectively with the pharmacy community and with society at large, such as, being able to comprehend and write effective reports, make effective presentations and documentation, and give and receive clear instructions.

PO - 9

The Pharmacist and society:  Apply reasoning informed by the contextual knowledge to assess societal, health, safety and legal issues and the consequent responsibilities relevant to the professional pharmacy practice.

 

COURSE OUTCOMES

PHARM D - Ist YEAR

1.3

Medicinal Biochemistry (THEORY)

CO - 1

Understood the importance of metabolism of substrates.

CO - 2

The students can able to acquire chemistry and biological importance of biological macromolecules

CO - 3

Students have acquired knowledge in qualitative and quantitative estimation of the biological macromolecules.

CO - 4

Students Knows the interpretation of data emanating from a Clinical Test Lab.

CO - 5

Students knows how physiological conditions influence the structures and reactivity’s of biomolecules

 

 

1.3

Medicinal Biochemistry (PRACTICAL)

CO - 1

The students Understood the qualitative analysis of carbohydrates and proteins

CO - 2

The students Understood the principle and clinical significance of blood glucose

CO - 3

Students can able to Identify the amount of reducing sugars by DNSA method

CO - 4

Students can able to Examine the constituents present in Urine and their clinical significance

CO - 5

Students can able to Determine the effect of temperature and substrate concentration on salivary amylase activity

 

PHARM D - Ist YEAR

1.4

Pharmaceutical Organic Chemistry (THEORY)

CO - 1

The students can able to give systematic names to simple organic compounds and polyfunctional groups.

CO - 2

The students can achieve an understanding of the behavior of organic compounds and establish a foundation for studies into natural and synthetic products of pharmaceutical interest

CO - 3

The students have acquired knowledge and understanding of the basic experimental principles of pharmaceutical organic chemistry

CO - 4

The students can able to Draw the structures and synthesize simple pharmaceutically active organic compounds

CO - 5

The students can able to describe detailed mechanisms for common reactions

 

 

1.4

Pharmaceutical Organic Chemistry (PRACTICAL)

CO - 1

Gained knowledge on different re-crystallization and steam distillation techniques

CO - 2

The students can able to remember and recall the different laboratory techniques used in pharmaceutical chemistry.

CO - 3

The students can able to Identify the purity of fats and oils by acid value, saponification value and iodine value.

CO - 4

Performed various reaction like diazotization, oxidation reactions.

CO - 5

Can Analyze named reactions like perkin and 11chmidt 11chmidt reactions by using carbonyl compounds.

 

PHARM D - Ist YEAR

1.5

Pharmaceutical Inorganic Chemistry (THEORY)

CO - 1

Students can well acquainted with the principles of limit tests.

CO - 2

Understood the principles and procedures of analysis of drugs and also regarding the application of inorganic pharmaceutical.

CO - 3

The students have knowledge about the sources of impurities and methods to determine the impurities in inorganic drugs and pharmaceuticals

CO - 4

Appreciate the importance of inorganic pharmaceuticals in preventing and curing the disease

CO - 5

The students have been introduced to a variety of inorganic drug classes

 

 

1.5

Pharmaceutical Inorganic Chemistry (PRACTICAL)

CO - 1

Can able to recall the sources of limit tests, preparation and identification of compounds.

CO - 2

Can able to prepare the inorganic pharmaceuticals.

CO - 3

Can Perform volumetric analysis such as acidimetric and alkalimeter, oxidation and reduction, complex metric, precipitation and non-aqueous titration

CO - 4

Can able to analyze various inorganic pharmaceutical compounds.

CO - 5

Can able to estimate the mixtures of inorganic compounds

 

PHARM D - 3rd YEAR

3.2

Pharmaceutical Analysis (THEORY)

CO - 1

The students can able to explain the basic concepts of quantitative and qualitative   analysis.

CO - 2

The students can able to explain principles and applications of aqueous, non- aqueous titrimetric methods to evaluate purity of drugs.

CO - 3

The students can able to describe principles and applications of volumetric and electro chemical analysis methods to evaluate purity of drugs

CO - 4

The students can able to explain principles and applications of redox titrations involved in the quantitative analysis of drugs.

CO - 5

The students can able to describe principles and applications of complexometric  and precipitation titrations to evaluate purity of drugs

 

 

3.2

Pharmaceutical Analysis (PRACTICAL)

CO - 1

The students can be able to estimate the amount of drugs present in the pharmaceutical products using colorimetric, UV visible and Fluorometric

principles.

CO - 2

The students can be able to studied the ions     throughflame photometry and nephelo turbidometry methods

CO - 3

The students can be able to separate and evaluate the natural products using paper, thin layer chromatography and column chromatography techniques

CO - 4

The students can be able to demonstrate of instrument handling

CO - 5

The students have Knowledge on ICH Guidelines

 

PHARM D - 3rd YEAR

3.5

Medicinal Chemistry (THEORY)

CO - 1

Understood the chemistry of drugs with respect to their biological activity.

CO - 2

knows the metabolism, adverse effect and therapeutic activity of drugs

CO - 3

Understood the different modern techniques of drug design

CO - 4

Appreciate the SAR of some important drug classes

CO - 5

The students have acquired knowledge in the chemotherapy for cancer and microbial diseases and different anti-viral agents

3.5

Medicinal Chemistry (PRACTICAL)

CO - 1

The students can able to synthesis drugs and intermediates like Sulphanilamide,  tolbutamide

CO - 2

The students can find out the amount and percentage purity of synthesized drugs

CO - 3

Can able to recall the basic requirements for synthesis and assay of drugs

CO - 4

Students has the knowledge about Drawing structures and reactions using chem draw

CO - 5

Students have learnt the physicochemical properties of drug by using molecular docking

 

B.PHARM

PROGRAMME EDUCATIONAL OUTCOMES (PEOs)

PEO - 1

To produce pharmacy graduates with strong basics and high technical knowledge to cater the various areas of Pharmaceutical Industry.

PEO - 2

Graduates will be able to discharge the responsibilities of pharmacist with adequate understanding of supportive area as needed in this multidisciplinary area of health care system.

PEO - 3

Pharmacists will be able to a part of the team to communicate well with other professionals in providing medicines needed to society with standards, professional ethics and social responsibilities.

PROGRAMME SPECIFIC OUTCOMES (PSOs)

PSO - 1

Apply the knowledge of pharmaceutical and allied sciences in design, manufacture and evaluation of drug delivery systems including cosmetics.

PSO - 2

Appreciate the mechanism of action of drugs including their kinetics and adverse actions. Be able to do basic evaluation of bioactivity of drugs in in - silico models.

 

PROGRAMME OUTCOMES (PO)

B.PHARM

PO - 1

Domain Knowledge: Demonstrate comprehension of basic principles of pharmaceutical and allied sciences in all pertinent scenarios. Exhibit skills associated with the profession of pharmacy, pharmaceutical manufacturing practices and quality control.

PO - 2

Problem analysis: Use domain knowledge, analytical and critical thinking for solving problems and taking decisions during everyday practice in profession, industry and all work environment.

PO - 3

Research and Development: Exhibit knowledge from his major domain in problem identification, critical thinking, analysis and providing solutions to pharmaceutical and allied technology disciplines.

PO - 4

Modern tools usage: Demonstrate an ability to handle/use various tools, apparatus, instrument, equipment or machinery pertinent to the pharmaceutical domain with practical knowledge on standard operating procedures and safety aspects.

PO - 5

The Pharmacist and Society: Use contextual knowledge – informed reasoning to understand medical prescription, perform patient counseling. Recognize the necessity to engage in independent and life-long learning.

PO - 6

Environment and sustainability: Demonstrate knowledge and responsibility while handling pharmaceutical techniques/ processes that have social and environmental impacts and promote sustainable development.

PO - 7

Ethics: Demonstrate exemplary professional, ethical, and legal behaviors in accordance with all drug, pharmaceutical, and pharmacy-related central, state laws and regulations.

PO - 8

Individual and Team skills: Function effectively as an individual member or leader in different teams and multidisciplinary settings. Assume a participatory or lead role in an organization’s planning and execution of transformational projects to enhance its prospects.

PO - 9

Communication: Communicate effectively with the pharmaceutical scientific community, work- force and with society at large, with abilities to comprehend and write effective reports, make effective presentations and documentation.

PO - 10

Project management abilities: Demonstrate effective delegation and organizational skills. Organize work with necessary planning and execution to meet deadlines. Demonstrate knowledge and understanding of pharmaceutical, legal processes and apply them in project management.

  

COURSE OUTCOMES

B.PHARM  YEAR - I (SEMESTER - I)

BP102T

Pharmaceutical Analysis I – Theory

CO - 1

The subject provides enough knowledge on basic concepts of quantitative and

qualitative analysis.

CO - 2

The subject provides enough knowledge on principles and applications of aqueous, non-aqueous titrimetric methods to evaluate purity of drugs.

CO - 3

The students learnt principles and applications of volumetric and electro chemical analysis methods to evaluate purity of drugs

CO - 4

The subject provides enough knowledge on principles and applications of redox titrations involved in the quantitative analysis of drugs.

CO - 5

The students has enough knowledge on principles and applications of complexometric and precipitation titrations to evaluate purity of drugs

BP108P

Pharmaceutical Analysis I – Practical

CO - 1

The students can able to: prepare and standardize solutions with different strength.

CO - 2

Can Perform volumetric analysis such as acidimetric and alkalimeter, oxidation and reduction, complex metric, precipitation and non-aqueous titration

CO - 3

understood the history and concept of pharmacopoeia and its editions

CO - 4

Gained knowledge on limit tests of different pharmaceutical inorganic compounds

CO - 5

Perform electro-Analytical methods

 

B.PHARM  YEAR - I (SEMESTER - I)

BP104T

Pharmaceutical Inorganic Chemistry – Theory

CO - 1

Understood the history and concept of pharmacopoeia and its editions.

CO - 2

knows the sources of impurities and methods to determine the impurities in inorganic

pharmaceuticals

CO - 3

Gained knowledge on limit tests of different pharmaceutical inorganic compounds

CO - 4

Understood the method to prepare inorganic pharmaceuticals.

CO - 5

Can able to justify the medicinal importance of acidifiers, antacids, cathartics and antimicrobial agents as gastrointestinal agents.

BP110P

Pharmaceutical Inorganic Chemistry – Practical

CO - 1

Can able to recall the sources of limit tests, preparation and identification of compounds.

CO - 2

Can able to prepare the inorganic pharmaceuticals.

CO - 3

Can able to apply knowledge to perform modified limit tests.

CO - 4

Can able to analyze various inorganic pharmaceutical compounds.

CO - 5

Can able to select suitable method for the preparation of inorganic pharmaceuticals

 

B.PHARM - YEAR - I (SEMESTER - II)

BP202T

Pharmaceutical Organic Chemistry I – Theory

CO - 1

Can write the structure, name of the organic compound and Knowledge about the naming reactions of carbonyl compounds

CO - 2

Has the knowledge about the type of isomerism

CO - 3

Can write the reaction, name the reaction and orientation of reactions

CO - 4

Can able to account for reactivity/stability of compounds

CO - 5

Can able to identify/confirm the unknown organic compound

BP208P

Pharmaceutical Organic Chemistry I– Practical

CO - 1

Can able to do Systematic qualitative analysis of unknown organic compounds

CO - 2

Preliminary analysis like color, nature of the compounds, saturated /unsaturated , Aliphatic/aromatic compounds, special elements

CO - 3

Can able to find Detection of elements like Nitrogen, Sulphur and Halogen by Lassaigne’s test and functional group analysis(carbonyl compounds, acids, aromatic aldehyde, esters & amines

CO - 4

Has the knowledge about Melting point/Boiling point of synthesized organic compounds

CO - 5

Can able to Prepare suitable solid derivatives from organic compound

 

B.PHARM - YEAR - I (SEMESTER - II)

BP203T

Biochemistry – Theory

CO - 1

Can able to write the properties, significance and metabolic reactions of

carbohydrates, lipids, nucleic acids, proteins and amino acids

CO - 2

Understood the metabolism of carbohydrates and process of electron transport and ATP formation

CO - 3

Learned the concept of catalytic activity and enzyme inhibition in design of new drugs, diagnostic and therapeutic applications of enzyme

CO - 4

Students can able to Distinguish the process of DNA replication, transcription and translation

CO - 5

The subjects provided knowledge on Appraise the causes, manifestations and

diagnosis of metabolic disorders

BP209P

Biochemistry – Practical

CO - 1

The students Understood the qualitative analysis of carbohydrates and proteins

CO - 2

The students Understood the principle and clinical significance of blood glucose

CO - 3

Students can able to Identify the amount of reducing sugars by DNSA method

CO - 4

Students can able to Examine the constituents present in Urine and their clinical

significance

CO - 5

Students can able to Determine the effect of temperature and substrate

concentration on salivary amylase activity

 

B.PHARM - YEAR - II (SEMESTER - III)

BP301T

Pharmaceutical Organic Chemistry II – Theory

CO - 1

Understood about aromaticity, chemistry and reactions of benzene

CO - 2

Understood the concept of hydrolysis, hydrogenation, saponification and rancidity of oils.

CO - 3

Gained knowledge on structure and medicinal uses of pharmaceutical organic

compounds.

CO - 4

Understood the concept of Baeyer’s theory and Sachse Mohr’s theory.

CO - 5

Gained knowledge on chemistry of phenols, aromatic amines and aromatic acids

BP305P

Pharmaceutical Organic Chemistry II – Practical

CO - 1

Gained knowledge on different recrystalization and steam distillation techniques

CO - 2

The students can able to remember and recall the different laboratory techniques used in pharmaceutical chemistry.

CO - 3

The students can able to Identify the purity of fats and oils by acid value,

saponification value and iodine value.

CO - 4

Performed various reaction like diazotization, oxidation reactions.

CO - 5

Can Analyze named reactions like perkin and claisen schmidt reactions by using carbonyl compounds.

 

B.PHARM - YEAR - II (SEMESTER - IV)

BP401T

Pharmaceutical Organic Chemistry III– Theory

CO - 1

Understood the nomenclature, properties and methods of preparation of

heterocyclic compounds.

CO - 2

Understood the fundamentals of stereo chemical aspects

CO - 3

Identify medicinal uses and other applications of organic compounds

CO - 4

Ability to explain stereo isomerism in biphenyl compounds (atropisomerism) and conditions for optical activity

CO - 5

Students Knows the reactions and synthetic importance of metal hydride reduction (NaBH4 & LiAlH4), Clemmensen reduction, Oppenauer oxidation and Beckmann rearrangement.

 

B.PHARM - YEAR - II (SEMESTER - IV)

BP402T

Medicinal Chemistry I – Theory

CO - 1

The students can able to recall the various classes of medicinal compounds

CO - 2

Can able to write the physicochemical properties, steric aspects of drugs and their metabolic pathways

CO - 3

The students gained knowledge on identify the structural requirements of drugs to elicit biological response

CO - 4

The students can able to categorize the drugs based on their mechanism of action and clinical uses

CO - 5

Gained knowledge on design the synthetic routes for medicinal compounds

BP406P

Medicinal Chemistry I – Practical

CO - 1

Can able to recall the basic requirements for synthesis and assay of drugs

CO - 2

Can able to write the techniques involved in isolation and purification of drugs

and intermediates

CO - 3

Gained knowledge on synthesize, characterize and purify medicinal compounds and intermediates

CO - 4

The students can able to Analyze the selected drugs present in dosage forms and to determine the percentage purity

CO - 5

Ability to explain the physicochemical property of drugs and draw its importance

 

YEAR - III (SEMESTER - V)

BP501T

Medicinal Chemistry II – Theory

CO - 1

The students have ability to recall the classification of drugs obtained by natural and synthetic route

CO - 2

knows the biological targets for medicinal compounds

CO - 3

Gained the knowledge of biochemical processes to understand the mechanism of action and therapeutic uses of drugs

CO - 4

Understood the relationships between structure of compound and its activity

CO - 5

Learnt Synthetic route for selected category of drugs

 

YEAR - III (SEMESTER - V)

BP505T

Pharmaceutical Jurisprudence – Theory

CO - 1

Understand the pharmaceutical legislation and implications in the development and marketing of pharmaceuticals

CO - 2

Study  of  Pharmacy Act, Medicinal and Toilet Preparation Act, Narcotics and Psychotropic Substances Act, Features of Drugs and Magic Remedies Act and

Medical Termination of Pregnancy Act

CO - 3

Study Prevention of Cruelty to animals Act, National Pharmaceutical Pricing Authority and Right to Information Act

CO - 4

Understand the concept of Intellectual property rights and Right to information act

CO - 5

Describe the codes of Pharmaceutical ethics during the pharmaceutical practice

 

B.PHARM - YEAR - III (SEMESTER - VI)

BP601T

Medicinal Chemistry III – Theory

CO - 1

The subject provides enough knowledge on Develop an understanding of the

physico-chemical properties of drugs.

CO - 2

Understood how current drugs were developed by using pharmacophore modeling and docking technique

CO - 3

Acquired knowledge in the chemotherapy for cancer and microbial diseases and different anti-viral agents

CO - 4

Acquired knowledge about the mechanism pathways of different class of

medicinal compounds

CO - 5

Introduced to a variety of drug classes and some pharmacological properties

BP607P

Medicinal chemistry III – Practical

CO - 1

The students can able to synthesis drugs and intermediates like Sulphanilamide, tolbutamide

CO - 2

The students can find out the amount and percentage purity of synthesized drugs

CO - 3

Students have learnt microwave irradiation techniques for prepare the medicinal compounds

CO - 4

Students has the knowledge about Drawing structures and reactions using chem

draw

CO - 5

Students have learnt the physicochemical properties of drug by using molecular docking studies

 

B.PHARM - YEAR - III (SEMESTER - VI)

BP606T

Quality Assurance –Theory

CO - 1

The students should be able to explain the general principle, importance and validation of instruments.

CO - 2

The students should be able to explain the elements and guidelines of Total Quality Management(TQM), ICH and Quality by design (QbD )aspects

CO - 3

The students should be able to describe the construction and plant lay out of organization and in a pharmaceutical industry

CO - 4

The students should be able to explain the procedures and guidelines for the Quality Control and Good Laboratory Practices

CO - 5

The students should be able to describe the importance and evaluation of document maintenance

 

B.PHARM - YEAR - IV (SEMESTER - VII)

BP701T

Instrumental Methods of Analysis – Theory

CO - 1

Students Can able to describe the principle, instrumentation and pharmaceutical

applications of interactions of electro magnetic radiations with drugs

CO - 2

Students Can able to describe the principle, instrumentation and applications of

vibrational spectrophotometric drug analysis

CO - 3

Students Can able to describe the principle and applications of chromatographic separation in drug analysis

CO - 4

Can able to describe the principle, instruments and applications of gas and liquid chromatographic separation in drug analysis

CO - 5

Can able to describe the principle and applications of electrophoretic techniques

BP705P

Instrumental Methods of Analysis – Practical

CO - 1

The students can be able to estimate the amount of drugs present in the pharmaceutical products using colorimetric, UV visible and Fluorometric principles.

CO - 2

The students can be able to studied the ions   through flame photometry and nephelo turbidometry methods

CO - 3

The students can be able to separate and evaluate the natural products using paper, thin layer chromatography and column chromatography techniques

CO - 4

The students can be able to demonstrate of instrument handling

CO - 5

The students have Knowledge on ICH Guidelines

 

B.PHARM - YEAR - IV (SEMESTER - VII)

BP706PS

Practice School

CO - 1

To understand the importance of realistic learning through practice in various domains such as community pharmacy, drug testing and manufacturing, preclinical testing, clinical practice, patent filing, regulatory filing accounting, green audit and article writing.

CO - 2

To get familiarize with the aspects of realistic practice in the domain of interest.

CO - 3

To develop knowledge and skills related to practical learning in the domain of interest.

CO - 4

To analyze the problems encountered during realistic practice and make use of theoretical knowledge to resolve those problems.

CO - 5

To build up the ability to perform well in the domain of interest after becoming an employee/entrepreneur.

 

B.PHARM - YEAR - IV (SEMESTER - VIII)

BP811ET

Advanced Instrumentation Techniques

CO - 1

Gained detailed knowledge on the principle, instrumentation and applications of NMR and mass spectroscopy methods in the drug analysis and drug discovery.

CO - 2

The students can able to Explain the principle, instrumentation and applications of thermal and X-ray diffraction methods in the drug analysis and drug discovery

CO - 3

The students can able to describe the ICH and USFDA guidelines for the calibration and validation of instruments

CO - 4

The students can able to describe the principle, instrumentation and applications of radioimmune assay in the drug analysis and drug discovery

CO - 5

The students can able to Explain the principle, instrumentation and applications of hyphenated techniques in the drug analysis and drug discovery

 

B.PHARM - YEAR - IV (SEMESTER - VIII)

BP813PW

Project Work

CO - 1

  Know the source of literature and literature survey

CO - 2

Able to design research protocol and carry out study as per design

CO - 3

Can analyze and interpret research data using appropriate statistical tools

CO - 4

Capable of writing scientific documents

CO - 5

Developed tendency to work in group

Publication

PUBLICATIONS

Title of paper

Name of the authors

Name of the Journal

Year of publications

ISSN NUMBER

A simple Spectrometric Determination of Albendazole from its Dosage forms.

Dr.Senthil Kumar.N

Eastern Pharmacist.

1998

2212-8872

Potent in Vitro Cytotoxicity Activity and antioxidant activity of Carea Arborea bark Extracts.

Dr.Senthil Kumar.N

Phytother Research.

2007

1099-1573

Antitumor activity and Antioxidant status of the methanol extract of Carea Arborea bark against DLA induced Ascetic and solid tumor in mice.

Dr.Senthil Kumar.N

Journal of pharmacology Science.

2007

381-391(2005)

Antioxidant and Hepatoprotective status of the methanol extract of Carea Arborea bark against ECA bearing mice.

Dr.Senthil Kumar.N

Journal of Natural Medicine.

2008

2224-3186

Antitumor activity of the Methanol extract of Hypericum hookerianum stem against Ehrlich Ascites Carcinoma in Swiss Albino Mice

Dr.Senthil Kumar.N

Journal of pharmacology Science.

2007

381-391

In vitro Antioxidant and Anti microbial activity of ethyl acetate extract of Evodialunu ankenda (gaertn) Merr.Bark

Dr.Senthil Kumar.N

Research Journal of Pharmacognosy and Phytochemistry.

2009

0975-2331

Antioxidant Activity of the Methanolic extract of Hypericum hukerianum stem .

Dr.Senthil Kumar.N

Pharmacology and thera

2010

2278-2656

Evaluation of diuretic activity of Samanea saman (Jacq) Merr bark in albino rats.

Dr.Senthil Kumar.N

Journal of Global Trends in Pharmaceutical Sciences.

2010

0976-8157

 Evaluation of Diuretic activity on Methanolic extract of Cajanus cajan (linn.)

Dr.Senthil Kumar.N

Journal of Pharmacy Research

2010

0974-6943

In vitro anthelmintic activity of Samanea saman (Merr) bark.

Dr.Senthil Kumar.N

Journal of Pharmacy Research

2010

0974-6943

CNS activity of ethanol extracts Wedelia chinensis in experimental animals.

Dr.Senthil Kumar.N

International journal of pharmaceutical sciences and nanotechnology

2010

0974-3278

Antibacterial activity of Methanolic root extract of Passiflora foetida Linn

Dr.Senthil Kumar.N

Journal of Pharmaceutical Sciences and Research

2010

0974-8232

A study of drug-drug interactions in prescriptions received at selected community pharmacies in Tamil Nadu

Dr.Senthil Kumar.N

Int. J. Res. Pharm. Sci.

2010

0022-3549

Assessment of health complaints and use of medicines among adolescents in Tamil Nadu

Dr.Senthil Kumar.N

Journal of Pharmacy Research

2010

0974-6943

Anti-hyperglycemic and anti-lipidemic activity of ethanolic extract of Bauhinia tomentosa (Linn) flower in normal and Streptozotocin- induced diabetic rats

Dr.Senthil Kumar.N

Journal of global pharma technology.

2010

0975-8542

In Vitro Antioxidant of Chloroform Extract of Areal Parts of Clerodendrum Inerme (1) Gaertn.

Mr.R.Vijayamirtharaj

Journal of Pharmacy Research.

2010

0974-6943

Method Development and Validation of RP-HPLC method for Simultaneous Determination of Lamivudine and Zindovudine.

Mr.R.Vijayamirtharaj

Journal of Chemistry Research.

2010

1747-5198

Studies on Anti-Inflammatory and Analgesic Properties of Methanol Extract of Aerial Part of Clerodendrum Inerme in Experimental animal method.

Mr.R.Vijayamirtharaj

Journal of Pharmocognosy and Phytochemistry.

2010

0975-2331

Analytical method development and validation of a new RP-HPLC method for estimation of Duloxetine hcl in capsule dosage form.

Mr.R.Vijayamirtharaj

Journal of Global Trends in Pharmaceutical Sciences.

2011

2230-7346

New RP-HPLC method Development and validation for estimation of Levofloxacin in tablet dosage form.

Mr.R.Vijayamirtharaj

Journal of Global Trends in Pharmaceutical Sciences.

2011

2230-7346

Simultaneous Equation Method for the Estimation of Lamivudine,Nevirapine and Zidovudine in Bulk and Tablets Dosage Forms.

Mr.R.Vijayamirtharaj

Journals of Pharmaceutical Chemistry.

2014

2394-2789

Development and Validation of RP-HPLC and UV method for ERLOTINIB Hydrochloride tablets.

Mr.R.Vijayamirtharaj

Journals of Comprehensive and Advanced Pharmacology.

2021

2456-9542

Method Development and Validation for the Simultaneous estimation of Lamivudine,Nevirapine and Zidovudine in bulk and tablet formulation by HPTLC method.

Mr.R.Vijayamirtharaj

International Journal of Pharmaceutical and Health Care Research.

2014

2249-5738

Hepatoprotective activity of ethyl acetate extract of aerial part of elerodendrum Phlomidis Linn in Paracetomal induced Hepato-toxic in Albino Rats.

Mr.R.Vijayamirtharaj

International Journal of Pharmatech Research.

2011

2455-9563

In-Vitro antioxidant and antimicrobial activities of Ethyl acetate extract of Evodialunu-ankenda(Gaertn)Merr.Bark

Dr T.Venkatachalam

Research Journal of Pharmacognosy and Phytochemistry

2008-2009

2278-4136

Evaluation of Analgesic activity of Evodia lunu-ankenda (Gaertn) Merr. Bark

Dr T.Venkatachalam

Der Pharmacia Sinicia

2009-2010

0976-8688

Phytochemical screening and antidiabetic potentially of Pavettaindica I(Angioperms:Rubiaceae)
methanol extract on Streptozocin induced diabetic mice

Dr T.Venkatachalam

Annals of Phytomedicine

2021-2022

2393-9885

Focus on the multimodal role of autophagy in Rheumatoid arthritis

Dr T.Venkatachalam

Inflammation

2020-2021

1178-7031

Understanding the possible rloe of endocannabinoid syste m in obesity

Dr T.Venkatachalam

Prostaglandins & other lipid mediators

2020-2021

1098-8823

The endocannabinoid singnaling pathway emerging targeting pharmacotherapy, earmarking mitigation
of destructive events in rheumatoid arthritis

Dr T.Venkatachalam

Life science

2019-2020

0024-3205

Pleotropic effects of polyphenols in cardiovascular system

Dr T.Venkatachalam

biomedicine &Pharmacotheraphy

2019-2020

0953-3322

Evaluation of anti-inflammatory and anti-diabetic activities of actinodaphne madras patana
bedd leaves

Dr T.Venkatachalam

Research journal of pharmacy and technology

2019-2020

0974-3618

Potency of unripe and ripe express extracts of long pepper(capasiumfrutisences bar baccatum)
aganist some common pathogens

Dr T.Venkatachalam

International journal of Pharmaceutical and phytochemical research

2018-2019

0975-4873

Preliminary phytochemical and physiochemical investigation of Woodfordiafruticosa (linn)
kurz root

Dr T.Venkatachalam

International journal of Green pharmacy

2017-2018

0973-8258

Pharmacological models to appraisement of antianxiety activity in experimental animals

Dr T.Venkatachalam

International journal of Green pharmacy

2017-2018

0973-8258

Computational investigation of binding mechanism of substituted pyrazinones targeting corticotropin
releasing factor-1 receptor deliberated for anti-depressant drug design

Dr T.Venkatachalam

Journal of Biomolcular structure and dynamic

2017-2018

1538-0254

New Spectrophotometric Method Applied to the Simultaneous Determination of Metoprolol and Hydrochlorthiazide

Dr T.Venkatachalam

Asian Journal of Research Chemistry

2009-2010

2456-7795

A simple HPLC method for Quantitation of Diacerin in Tablet Dosage form,Eurasian

Dr T.Venkatachalam

Journal of Analytical Chemistry

2009-2010

1608-3199

RP-HPLC Method for Simultaneous Determination of Pioglitazone and Telmisartan in Tablet Dosage Form

Dr T.Venkatachalam

Asian Journal of Research Chemistry

2009-2010

2456-7795

Pharmacological Evaluation of Clerodendrum Philippinum Schauer Flower of Antianxiety and Central nervous system depressant activity

Dr T.Venkatachalam

 International Journal of pharmaceutical Research,

2009-2010

April - June

2454-8405

HPTLC Method for Simultaneous Determination of Pioglitazone HCL and Telmisartan inTabletDosageform

Dr T.Venkatachalam

AsianJournalofResearchChemistry

2009-2010

Jan-Mar

0974-4169

Physico-chemical and Preliminary Phytochemical Studies onthe

Lantana Camara Linn Fruits

Dr T.Venkatachalam

International Journal of Pharmacy and Pharmaceutical Science

2010-2011

Jan-Mar

0975-1491

In Vitro Evaluation of Antioxidant Activity of Blue Green Algae Spirulina Platensis

Dr T.Venkatachalam

International Journal of Pharmaceutical Science and Research

2010-2011

Oct

0975-1491

Pharmacognostical and Phytochemical Studies of The Leaves of Albizia Odoratissima (L.F) Benth

Dr T.Venkatachalam

International Journal of Pharmacognosy and Phytochemical Research

2010-2011

Oct-Nov

0975-4873

Simulataneous estimation of Melatonin and Zolpidem in Tablets dosage forms by RP-HPLC Method

Dr T.Venkatachalam

International journalof biological & Pharmaceutical Research

2008-2009

June

0976-3651

Prospective study on effectiveness of H.Pylori radication therapy and utilization of acid suppressant medications in patients with pepticulcer disease

Dr T.Venkatachalam

International journal of applied pharmaceutical and Biological research

2015-2016

0976-3651

Assesment of efficacy of Aceclofenac versus Tramadol in osteoarthritis patients

Dr T.Venkatachalam

International journal of applied pharmaceutical and Biological research

2015-2016

0976-3651

Evaluation of prescribing pattern of antiepileptic drugs in Epilepsy

Dr T.Venkatachalam

International journal of applied pharmaceutical and Biological research

2015-2016

0976-3651

Assessment of poly pharmacy among the Geriatric poulaation in a tertiory care hospital in Kerala;A prospective study

Dr T.Venkatachalam

International journal of applied pharmaceutical and Biological research

2015-2016

0976-3651

Preliminary phytochemical and physiochemical investigation og Woodfordia fruticosa (linn) Kurz root

Dr T.Venkatachalam

International Journal of Green pharmacy

2017-2018

Oct-Dec

0973-8258

Justice Oyindeinyefa Epidi, and Roopam Devaliya

Dr T.Venkatachalam

International Journal of Pharmaceutical and Phyto pharmacological Research

2018-2019

2249-6084

In-Vitro antioxidant and antimicrobial activities ofEthyl acetateextractofEvodialunu-ankenda(Gaertn)Merr.Bark

Dr T.Venkatachalam

Research Journal of Pharmacognosy and Phytochemistry,

2008-2009

Nov - Dec

2278-4136

New Spectrophotometric Method Applied to the Simultaneous Determination of Metoprolol and Hydrochlorthiazide

Dr T.Venkatachalam

Asian Journal of Research Chemistry

2009-2010

April -June

0974-4169

A simple HPLC method for Quantitation of Diacerin in Tablet Dosage form,Eurasian

Dr T.Venkatachalam

Journal of Analytical Chemistry

2009-2010

1608-3199

RP-HPLC Method for Simultaneous Determination of Pioglitazone and Telmisartan in Tablet Dosage Form

Dr T.Venkatachalam

 Asian Journal of Research Chemistry

2009-2010

July-Sep

0974-4169

Anti-Ulcer Evaluation of Methanolic Extract of Rhinacanthus nasutus Linn Kurz

Dr T.Venkatachalam

International Journal of Research in Pharmaceutical and Biomedical Sciences

2010-2011

Jul-Sep

2229-3701

Pharmacological Evaluation of Clerodendrum Philippinum Schauer Flower of Antianxiety and Central Nervous system Depressant Activity

Dr T.Venkatachalam

International Journal of pharmaceutical Research

2009-2010

Apr-June

0975-2366

HPTLC Method for Simultaneous Determination of Pioglitazone HCL and Telmisartan inTabletDosageform

Dr T.Venkatachalam

AsianJournalofResearchChemistry

2009-2010

Jan-Mar

0974-4169

Physico-chemical and Preliminary Phytochemical Studies on the Lantana Camara Linn Fruits

Dr T.Venkatachalam

International Journal of Pharmacy and Pharmaceutical Science

2010-2011

Jan-Mar

0975-1491

In Vitro Evaluation of Antioxidant Activity of Blue Green Algae Spirulina Platensis

Dr T.Venkatachalam

International Journal of Pharmaceutical Science and Research

2010-2011

Oct

0975-1491

Pharmacognostical and Phytochemical Studies of The Leaves of Albizia Odoratissima (L.F) Benth

Dr T.Venkatachalam

International Journal of Pharmacognosy and Phytochemical Research

2010-2011

Sep-Nov

0975-4873

Simulataneous estimation of Melatonin and Zolpidem in Tablets dosage forms by RP-HPLC Method

Dr T.Venkatachalam

International journal of biological & Pharmaceutical Research

2008-2009

June

0976-3651

 Prospective study on effectiveness of H.Pylori radication therapy and utilization of acid suppressant medications in patients with pepticulcer disease

Dr T.Venkatachalam

International journal of applied pharmaceutical and Biological research

2015-2016

0976-3651

Assesment of efficacy of Aceclofenac versus Tramadol in osteoarthritis patients

Dr T.Venkatachalam

International journal of applied pharmaceutical and Biological research

2015-2016

0976-3651

Evaluation of prescribing pattern of antiepileptic drugs in Epilepsy

Dr T.Venkatachalam

International journal of applied pharmaceutical and Biological research

2015-2016

0976-3651

Assessment of poly pharmacy among the Geriatric poulaation in a tertiory care hospital in Kerala;A prospective study

Dr T.Venkatachalam

International journal of applied pharmaceutical and Biological research

2015-2016

0976-3651

Justice Oyindeinyefa Epidi, and Roopam Devaliya

Dr T.Venkatachalam

International Journal of Pharmaceutical and Phytopharmacological Research

2018-2019

2249-6084

Computational investigation of binding mechanism of substituted pyrazinones targeting corticotropin releasing factor-1 receptor deliberated for anti-depressant drug design

Dr T.Venkatachalam

Journal of Biomolecular structure and dynamics,

2017-2018

Dec

1538-0254

Pharmacological models to appraisement of antianxiety activity in experimental animals

Dr T.Venkatachalam

International Journal of Green pharmacy

2017-2018

Jul-sep

0973-8258

Pharmacological Activities of Daucus Carota Subs P. Sativus Extract on Streptozotocin Induced Diabetic Rats. Research

Dr T.Venkatachalam

Journal of Pharmaceutical, Biological and Chemical Sciences

July – August 2021

0975-8585

Analytical Method Development and Validation of Cefixime and Ofloxacin in Tablets by RP-HPLC Method

Dr T.Venkatachalam

J .of Indian Drugs

August 2012

2455-3972

Spectrophotometric methods for Simultaneous estimation of melatonin and zolpidem from the combined tablet dosage forms

Dr T.Venkatachalam

Pharmacophore

2014

2229-5402

High performance thin layer chromatographic method for the Simultaneous quantitation of melatonin and zolpidem in tablet formulations

Dr T.Venkatachalam

Journal of pharmaceutical research

2014

2456-9119

Evaluation of Anti-inflammatory and Anti- diabetic activities of Actinodaphne madraspatana bedd leaves

Dr T.Venkatachalam

Research j. pharma Tech

2010

2249-3387

Preparation and Evaluation of Ocuserts for increasing the bioavailability of an Antifungal Drugs

Dr T.Venkatachalam

Acta Scientific Pharmaceutical Sciences

October 2020

2581-5423

Immuno modulators against COVID-19

Dr T.Venkatachalam

International Journal of Pharmacy and Pharmaceutical Research

May 2020

2349-7203

Phytochemical screening and antidiabetic potentiality of Pavetta indica .L(angiosperms: rubiaceae) methanolextract on streptozotocin induced diabetic mice.

Dr P.Kalaiselvi

Neuroquantology

2022

1303-5150

Development and Evaluation of Anti-Inflammatory Gel containing Zinger Officinale

Dr P.Kalaiselvi

Annals of phytomedicine

2021

2393-9885

A review on the Therapeutic management of Covid-19 associated with thrombotic events and coiagulopathies

Dr P.Kalaiselvi

journal of Pharmaceutical research international

2022

2456-9119

A Naarative review on etiopathogenesis clinical manifestations and management of parapnemonic effusions with little insight on its diagnostic procedures

Dr P.Kalaiselvi

Neuroquantology

2022

1303-5150

Extraction and investigation of In vitroantioxidant and antimicrobial activity of acacia pennata

Dr P.Kalaiselvi

Neuroquantology

2022

1303-5150

 

The design ,synthesis and evaluation of Diaminopimelic acid derivatives as potential dapF inhibitors preventing lysine biosynthesis for ntibacterial activity

Dr P.Kalaiselvi

Antibiotics

2023

0021-8820

Simulataneous estimation of Ofloxacin and Nitazoxanide in Tablets by RP-HPLC Method

Dr P.Kalaiselvi

Indian Drugs

2009

june

2455-3972

Pharmacognostical and Preliminary Phytochemical studies on Algae Spirulina Platensis Nordst”,

Dr P.Kalaiselvi

Journal of Pharmacy Research,

November 2010

0974-6943

Evaluation of Analgesic activity of Evodia lunu-ankenda (Gaertn) Merr. Bark

Dr P.Kalaiselvi

Der Pharmacia Sinicia

2010

0976-8688

Antidiabetic activity of Lantana camara Linn fruits in normal and streptozotocin induced diabeticrats

Dr P.Kalaiselvi

JournalofPharmacy Research

May 2011

0974-6943

A New Analytical method development and validation for the simultaneousestimationof Ramipril,Atrorvastatin and Clopidogrel in Capsule dosage form by RP- HPLC

Dr P.Kalaiselvi

Journal of Pharmacy and Chemistry

July-Sept 2009

2575-5749

Anti inflammatory and Anti nociceptive activity of Pavonia Zeylanica Linn”

Dr P.Kalaiselvi

Asian J.Res Pharm.Sci,

2011

2231-5659

RP-HPLC method for simultaneous determination of Ofloxacin and Satranidazole in tablet dosage form

Dr P.Kalaiselvi

Asian journal of research chemistry

2012

0974-4169

Development and validation of HPTLCmethod for simultaneous estimation of Cefixime and Ofloxacin in their combinedtablet dosage form

Dr P.Kalaiselvi

Indian drugs

2015

2455-3972

Method cevelopment and validation of Hydrochlorothiazide, Amlodipine besylate and Telmisartan in tablet dosage formsb y RP-HPLC method

Dr P.Kalaiselvi

Research journal of pharmaceutical, biological and chemical sciences

2012

0975-8585

In-Vitro antioxidant and antimicrobial activities of

Ethyl acetate extract of Evodia lunu-ankenda (Gaertn) Merr.Bark

Dr P.Kalaiselvi

Research

Journal of Pharmacognosy and Phytochemostry

November

– December 2009

2278-4136

New Spectrophotometric Method Applied to the Simultaneous

Determination of Metoprolol and Hydrochlorthiazide

Dr P.Kalaiselvi

Asian Journal of Research

Chemistry

April – June 2010

0974-4169

A simple HPLC method for Quantitation of

Diacerin in Tablet Dosage form

Dr P.Kalaiselvi

Eurasian Journal of Analytical

Chemistry

2010

1306-3057

RP-HPLC Method for Simultaneous Determination of Pioglitazone and Telmisartan in Tablet Dosage Form

Dr P.Kalaiselvi

Asian Journal of Research Chemistry

July – September 2010

0974-4169

Pharmacological Evaluation of Clerodendrum

Philippinum Schauer Flower of Antianxiety and Central Nervous system

Depressant Activity

Dr P.Kalaiselvi

International Journal of pharmaceutical Research

2010,April-June 

0975-2366

HPTLC Method for Simultaneous Determination of Pioglitazone HCL and Telmisartan in Tablet Dosage form

Dr P.Kalaiselvi

Asian Journal of Research Chemistry

Jan-Mar 2010

0974-4169

Phytochemical screening and Antimicrobial Activity of Bauhinia tomentosa Linn Flower

Dr P.Kalaiselvi

Deccan Journal of Natural Products

October – December 2010

 

Physico-chemical and Preliminary Phytochemical Studies on the Lantana Camara Linn Fruits

Dr P.Kalaiselvi

International Journal of Pharmacy and Pharmaceutical Science,

January – March 2011

0975-1491

Simultaneous Spectrophotometeric Estimation Of Lafutidine And Domperidone In Solid Dosage Forms

Dr P.Kalaiselvi

International Journal of Pharmacy and Pharmaceutical Sciences

2014

0975-1491

Development And Validation Of Rp-Hplc Method For The Simultaneous Estimation Of Chlorthalidone And Irbesarton In Pharmaceutical Dosage Form

Dr P.Kalaiselvi

Pharmacophore (An International Research Journal)

2014

2229-5402

Simulataneous estimation of Ofloxacin and Nitazoxanide in Tablets by RP-HPLC Method

Dr P.Kalaiselvi

Indian Drugs

June 2009

2455-3972

Evaluation of Analgesic activity of Evodia lunu-ankenda (Gaertn) Merr. Bark

Dr P.Kalaiselvi

 Der Pharmacia Sinicia

2010

0976-8688

Antidiabetic activity of Lantana camara Linn fruits in normal and streptozotocin-induced diabetic rats

Dr P.Kalaiselvi

Journal of Pharmacy Research

May 2011

0974-6943

A New Analytical method development and validation for the simultaneous estimation of Ramipril,Atrorvastatin and Clopidogrel in Capsule dosage form by RP-HPLC

Dr P.Kalaiselvi

 Journal of Pharmacy and Chemistry

July-Sept 2009

2231-2781

Anti inflammatory and Anti nociceptive activity of Pavonia Zeylanica Linn

Dr P.Kalaiselvi

Asian J.Res Pharm.Sci

2011

2231-5659

Hptlc Methods Development and Validation For Simultaneous Estimation Of Chlorthalidone And Irbesartan Combined Tablet Dosage Form

Dr P.Kalaiselvi

J . of Indian Drugs

July 2014

2455-3972

Validated Hptlc Method for Simultaneous Estimation Of Lafutidine And Domperidone in a Tablet Dosage Form

Dr P.Kalaiselvi

Journal of Pharmaceutical Research

April - June 2014

2456-9119

Pharmacological evaluation of Ethanolic extract of leaves of Memecylon Kollimalavanum

Dr P.Kalaiselvi

American journal of pharmacy and health research

2018

2321-3647

Phytochemical screening and Antimicrobial Activity of Bauhinia Tomentosa Linn Flower

Dr.A.Chitra

Deccan Journal of Natural Products

2010

0976-0512

Evaluation of Antipyretic activity of ethanolic extract of Symplocos racemosa

Dr.A.Chitra

International Journal of Bioapplied Pharmaceuticals

2010

0975-7058

New RP-HPLC method development & validation for estimation of Levoflaxacin in tablet dosage form

Dr.A.Chitra

Journal of global trends in Pharmaceutical Sciences.

2011

2230-7346

Evaluation of Antimicribial activity of Catunaregum spinosa

Dr.A. Chitra

 International Journal of Pharmacology & Toxicology

2014

2249-7668

Antioxidant and antitumor activities on Catunaregum spinosa

Dr.A. Chitra

International Journal of Research in Pharmacology and Pharmacotherapeutics

2013

2278-2656

Anti-inflammatory, Analgesic and Antipyretic activity of methanolic extract of Catunaregum spinosa

Dr.A. Chitra

 International Journal of Phytopharmacology

2013

0975-9828

 Characterisation of Physalis lagascae for its Invitro anticancer activity

Dr.A. Chitra

European Journal of Pharmaceutical and Medical Research

2019

2394-3211

Antidiabetic activity of ethanolic extract of Baringtonia acutangula

Dr.A. Chitra

International Journal of Research in Pharmacology and Pharmacotherapeutics

2019

2278-2656

A review on novel Corona virus

Dr.A. Chitra

Journal of Allied Medical Sciences and Clinical Research

2020

2347-6567

 Formulation and Evaluation of fast dissolving oral film of Mefenamic acid

Dr.A. Chitra

International Journal of Pharmacy and Analytical Research

2020

2320-2831

Formulation and Evaluation of Polymeric Microspheres of Ferulic Acid By Molecular Docking Studies

Dr.A.Chitra

International Journal Frontiers in Science and Technology

2020

2020

2783-0446

Evaluation of Antipyretic activity of methanolic extract of Euphorbia cyathophora

Dr.M. Chitra

International Journal of Phytopharmacology

2013

0975-9328

Evaluation of Hepatoprotective and Antioxidant activity of Euphorbia cyathophora

Dr.M. Chitra

International Journal of Research in Pharmacology and Pharmacotherapeutics,

2013

2278-2656

 Antimicrobial and Wound healing activities of Euphorbia cyathophora

Dr.M. Chitra

 International Journal of Pharmacology Research

2014

2249-7641

Outbreak of Nipha virus in India

Dr.M. Chitra

International Journal of Pharmacology and Clinical Research

2018

2521-2206

 Formulation and Evaluation of fast dissolving oral film of Mefenamic acid

Dr.M. Chitra

International Journal of Pharmacy and Analytical Research

2020

2320-2831

A review on novel Corona virus

Dr.M. Chitra

International Journal of Allied Medical Sciences and Clinical Research

2020

2347-6567

In-Vitro antioxidant and antimicrobial activities of Ethyl acetate extract of Evodia lunu-ankenda (Gaertn) Merr.Bark

Dr.M. Chitra

 Research Journal of Pharmacognosy and Phytochemistry.

2009-2010

0975-2331

Synthesis and Biological Evaluation of Mannich Bases of 2-Subatituted Benzimdazoles

Dr.M.Chitra

Asian Journal of Chemistry

2009

0970-7077

Synthesis of 2-{(Bis- (2- chloroethyl )amino )acetamido } 5- substituted- 1,3,4- thiadiazole as possible alkylating Anticancer Agents

Dr.K.Sumathi

Asian journal of chemistry

2006

0970-7077

3-D QSAR CoMFA Study of Nitrogen Mustards Possessing New Chemical Entities as Possible Anticancer Agents

Dr.K.Sumathi

Indian Journal of Pharmaceutical Sciences

May- June 2006

1998-3743

Synthesis of Some 1- [Bis- N, N- (2- Chloroethyl ) Aminoacetyl }-3, 5- Disubstituted- 1,2- Pyrazolines as Possible Alkylating Anticancer Agents

Dr.K.Sumathi

Asian Journal Research Chemistry

April- June 2010

0970-7077

Pharmacological and Preliminary Phytochemical Studies

 of Jasminum trichotomum Leaves

Dr.K.Sumathi

Journal of Pharmacy Research

2011

2011

0974-6943

 Synthesis And Biological Evaluation of New S- Mannich Base of 3- Methyl – 4- Phenyl -3,4,5,6,7,8, Hexahydroquinazoline- 2(1 h)- Thione

Dr.K.Sumathi

Asian J. Research Chem

Oct, 2011

Oct, 2011

0974-4169

Invitro anti oxidant and free radical scavenging studies of Carissa carandas L

Dr.K.Sumathi

International Journal of Research in Pharmacology and Pharmacotherapeutics

2016

2249-7765

Invitro anti oxidant and free radical scavenging studies of Carissa spinarum L

K.Sumathi

International Journal of Allied Medical Sciences and Clinical Research

2016

2347-6567

anticancer activity of ethanolic fractions of Carissa carandas L

Dr.K.Sumathi

International Journal of Pharmacological Screnning Methods

2016

2249-7749

Invitro anticancer activity of methanolic fractions of Carissa spinarum L

Dr.K.Sumathi

International Journal of Pharmacology and Toxicology

2016

2249-7668

Free Radical Scavenging Activity.Invitro Screening of various extract of Barleria Noctiflora for their Antioxidant and free radical scavenging activity

Dr.K.Sumathi

Int. J. Pharm. Phytopharmacol Res

2015

2249-6084

Formulation and Evaluation of fast dissolving oral film of Mefenamic acid

Dr.K.Sumathi

International Journal of Pharmacy and Analytical Research

2020

2249-7781

Analytical method development and validation of simultaneously RP-HPLC estimation of Ornidazole and Ofloxacin in Tablets Dosage Forms

Mrs.B.Anbarasi

Journal of Pharmacy Research

2021

0974-6943

Hepatoprotective Activity of Ethanolic Extract of Tribulus Cistoides Against CCL4 Induced Hepatoxicity in Wister Male Rats.

Mrs.B.Anbarasi

International Journal of Pharmacology and Clinical Research.

2020

0974-9446

An Overview of Hyperlipidemia.

Mrs.B.Anbarasi

Der Pharmacia Lettre.

2021

0975-5071

Analytical Method Development and Validation of Amlodipine-an Antihypertensive and Chlorthalidone and –A Thiazide Diuretic by RP-UPLC Method.

Mrs.B.Anbarasi

International Journal of Chemical and Pharmaceutical Sciences.

2016

0975-7384

Hypolopidemic Activity Cissus Quadrangularis Linn in Ovariectomized Mice.

Mrs.B.Anbarasi

Turkish Journal of Pharmaceutical Sciences.

2022

2148-6247

Antioxidant and Antiinflammatory Activity of Zizyphus Jujuba Lam Leaves.

Mrs.B.Anbarasi

j. of Indian Drugs

2019

2455-3972

Antipyrutic activity of Zizyphus Jujuba Lam Leaves.

Mrs.B.Anbarasi

Journal of Advanced Scientific Research.

2012

0976-9595

Pharmacognostic and Preliminary Phytochemical evaluation of Zizyphus Jujuba Lam Leaves

Mrs.B.Anbarasi

World Journal of Pharmacy And Pharmaceutical Sciences.

2013

2278-4357

Hypoglycemic and Hypolipemic Activity of Zizyphus Jujube Lam Leaves in Streptozoztocin Induced Hyperglycemia.

Mrs.B.Anbarasi

Research Journal of Pharmaceutical, Biological and Chemical Sciences.

2014

0975-8585

Analytical Method Development and Validation of Cefixime and Dicloxacillin in Tablet Dosage form by RP-HPLC.

Mrs.B.Anbarasi

International Journal of Pharmaceutical Research and Development.

2010

0974-9446

Analytical Method Development and Validation of Galantamine HBr.in Capsule Dosage form by RP-HPLC.

Mrs.B.Anbarasi

International Journal of Pharmaceutical Research and Development.

2010

0974-9446

Analytical Method Development and Validation of Amlodipine and Hydrochlorothiazide in Combined Dosage form by RP-HPLC.

Mrs.B.Anbarasi

International Journal of Chemistry Tech Research.

2010

0974-4290

Analytical Method Development and Validation of Donepezil Hydrochloride by RP-HPLC and UV.

Mrs.B.Anbarasi

International Journal of Pharmacy and Technology.

2010

0974-3618

Lab Facilities

The following Laboratories available in Pharmaceutical Chemistry & Pharmaceutical analysis department.

 v   Pharmaceutical chemistry Laboratory-1

v   Pharmaceutical chemistry Laboratory-2

v   Pharmaceutical chemistry Laboratory-3

v   Pharmaceutical chemistry Laboratory-4

v   Pharmaceutical analysis Laboratory-1

v   Pharmaceutical analysis Laboratory-2

v   R & D Laboratory

 

 

Department photos

MOU

S.

NO

Academic year

Organization with which MoU is signed Date of Signing

Date of Signing

MOU Duration

1

2018-2019

COLUMBIA ASIA HOSPITAL, MYSURU

30/10/2018

5 Years

2

2019-2020

ATOZETA HEALTH SOLUTIONS PVT. LTD

01/10/2019

5 Years

3

2019-2020

FREEDOM CARE

27/09/2019

5 Years

4

2020-2021

CLINOSOL RESEARCH PRIVATE LIMITED

05/10/2020

5 Years

5

2021-2022

MAARUTHI MEDICAL CENTRE AND HOSPITALS,ERODE

19/01/2021

5 Years

Writeups

             The Department of Pharmaceutical Chemistry & Analysis is primarily involved in providing strong foundation in fundamentals of different branches of chemistry viz. Organic chemistry, Inorganic chemistry, Biochemistry, Medicinal Chemistry, Natural product chemistry and Analytical Chemistry. M. Pharm Pharmaceutical analysis started in 2007 and chemistry Branch was started in 2008.

      The objective of the department is to provide profound theoretical and practical knowledge to the students and to shape them into professionals with technical competence by intensive training.

Our mission is to instil confidence to our students by adopting an interactive teaching methodology through which they are made to understand the basics of chemistry and to create a conductive environment which would make them skilled chemists and analyst. Faculty of this department are well experienced and highly qualified with a dedication to teaching. The entire faculty have the exposure and opportunity to carry out research. The department has more than 50 original research articles published in reputed journals.

        The department has all basic and advanced features like well-ventilated spacious laboratories with water and gas connections, fume free environment, glass wares including custom designed vessels etc. The department has HPTLC, HPLC, FTIR and UV spectrophotometers, Digital melting point apparatus, microwave reactor, reaction dry bath, hot air oven, vacuum oven, digital mixers and stirrers, high end filtration equipment’s and other instruments to carry out research.

       The department has identified core areas of research mainly in medicinal chemistry in the fields of cancer, diabetes, inflammation and chemotherapy of microbial diseases. The prime motto of our research is to identify a lead molecule either of synthetic or natural origin and to optimize the lead to achieve desirable pharmacodynamics and pharmacokinetic properties. The methods to identify the lead applied in our department includes design, synthesis, SAR, characterization and screening of novel organic molecules using traditional as well as cutting edge technologies like high throughput screening and molecular modelling. Lead optimization is carried out using computational methods.

       Our strategy for achieving global standards  to develop a "Drug design and synthesis research laboratory" with excellent facilities at par with industrial standards and to possess accreditation of government research organizations, pharmaceutical industries and international standard organizations.

The Department of Pharmaceutical Analysis aspires to focus on the development of analytical methods that combine novel apparatus and approaches with existing ones. Basic research on the identity, purity, content, and stability of starting materials, excipients, and active medicinal substances is involved. The department teaches and trains postgraduate students in analytical sciences relevant to the qualitative and quantitative estimation of natural, synthetic substances and biological samples in various matrices using spectroscopy, chromatography, and analytical procedures.

Pharmaceutical Analysis is a branch of practical chemistry that involves a series of process for identification, determination, quantification and purification of a substance, separation of the components of a solution or mixture, or determination of structure of chemical compounds. The department of Pharmaceutical Analysis was established in the year 2007. The courses were designed to provide industry ready professionals for the analysis and quality control of pharmaceuticals with appropriate skill set, knowledge base and practical expertise. The department is also recognized for the conduct of Ph D research program. The research laboratory in the department is equipped with sophisticated analytical instruments like High Performance Liquid Chromatography (HPLC) with different detector configurations (Photo diode array detector, Dual Wavelength UV Detector and UV-VIS detectors), UV – VIS Spectrophotometer, FT- IR Spectrophotometer, Fluorimeters, Flame Photometers etc. The departmental activities are supported by well qualified and trained academicians

Thrust Areas:

ü  Analytical and Bio analytical method development and validation

ü  QbD based analytical method optimization

ü  Impurity Profiling

ü  Development and validation of stability indicating analytical methods

ü  Food and cosmetic analysis

ü  Application of green chemistry for rapid analysis of drugs

ü  Standardization of Herbal formulations

ü  Development and evaluation of drugs/ formulations for heavy metal toxicity.